RQ Biotechnology Ltd. Raises $115.

Vitalis Ortho

Knee osteoarthritis affects over 365 million people worldwide. For the 37% of patients under 65-years-old, established clinical pathways have limited options between pain management and joint replacement. That leaves millions in a treatment gap facing a particularly difficult trade-off: undergo a knee replacement and face a lifetime revision risk of 1 in 3, or delay surgery and lose years of quality life. Olly Morgan and Mac Tuncer spent years operating at the end of that journey. Together, they scaled Meshworks Implants into the UK and Ireland’s leading provider of personalised, 3D-printed orthopaedic implants. The devices were designed for the most complex revision cases, where standard implants had already failed. They exited the business in 2024. That experience gave them an unusually clear view of what goes wrong upstream. Vitalis Ortho was founded on a single conviction that the window for meaningful intervention exists years before irreversible surgery becomes the only option. Our goal is to make joint preservation the default for younger patients, not the exception.

Astral Systems

Based in Bristol, UK, Astral Systems was founded in 2021. Our Multi-State Fusion (MSF) reactor is a versatile, compact, and cost-effective solution for on-demand neutron production. We leverage cutting-edge fusion discoveries out of NASA and are continually advancing the effectiveness of our MSF technology. We offer high-flux neutron sources for decentralised and scale medical isotope production, nuclear power applications, and much more. Our first Mk1 product is now available for order with a fusion neutron performance that has a 10x higher output and over 10x longer lifetime than any compact neutron source on the planet.

Omni Pet | B Corp™

Pet food is usually made from unwanted, unhealthy animal by-products from the CO2 polluting meat industry. But it doesn’t have to be this way, omni has created delicious, healthier and more sustainable plant-based dog food.

Silveray

Developing next generation direct conversion X-ray detectors for healthcare, industrial, and security applications.

Isometric

Isometric is the agentic certification platform for the industrial economy. Its AI agents work alongside human verifiers, reviewing every data point so expert judgment is freed for the calls that matter, in place of the slow, manual reviews that have defined certification for decades. What used to take months now takes hours. From carbon removal and superpollutant reduction to low-carbon energy, fuels, and materials, Isometric brings them all onto a single platform, held to a single standard, with every certificate published on a single public Registry. Isometric is the largest certifier of carbon removal by contracted volume, trusted by Microsoft, Anglo American, JPMorganChase, and Boeing, and fully accredited by ICVCM, ICROA, and CORSIA.