OneOncology Acquired by TPG and Cencora, Bolstering Cancer Care
OneOncology acquired by TPG and Cencora
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OneOncology
Deal Value
USD2,100,000,000
December 15, 2025

TPG and Cencora
TPG and Cencora have acquired OneOncology for $2.1 billion.
This corporate acquisition sees the private equity firm and global healthcare solutions company take full ownership of OneOncology, a national partnership of independent community oncology practices.
The deal represents a significant strategic investment in the evolving landscape of community-based cancer treatment, clearly distinguishing it from a funding round for OneOncology.
OneOncology specializes in empowering independent community oncology practices across the United States.
Its model is patient-centric, physician-driven, and technology-powered, aiming to improve the lives of individuals living with cancer.
The company supports the entire continuum of care, from prevention and diagnosis to research, treatment, survivorship, palliative, and hospice care.
A key component of OneOncology's approach is its cloud-based network, which provides access to essential clinical and operational data, enabling practices to transition to value-based care and deliver best-in-class healthcare close to home.
The acquisition is strategic, leveraging OneOncology’s robust network and technological infrastructure.
Synergies are expected from combining OneOncology's capabilities in cancer care delivery and practice support with the strategic insights and resources of TPG, alongside Cencora's extensive reach in healthcare solutions.
This integration aims to enhance operational efficiencies, expand access to advanced cancer care, and further accelerate the adoption of value-based care models within community oncology settings.
The combination allows for deeper investment into OneOncology's mission without being a fundraising event.
Looking ahead, the combined entity is positioned to accelerate innovation in community cancer care.
By strengthening the support available to independent oncology practices, the acquisition is anticipated to drive advancements in patient outcomes, improve practice operations, and reinforce the critical role of local oncology care in the broader healthcare ecosystem.
This strategic alignment underscores a collective commitment to transforming cancer treatment for patients nationwide.
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